JOURNAL OF CONTEMPORARY DISEASES AND ADVANCED MEDICINE
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ANALYSIS OF LARYNGEAL ALTERATIONS IN PATIENTS AFTER SARS-COV-2 INFECTION

Edition V01N2  |  Year 2022  |  Category: Research Article  |  Page 114 to 122

Autors

Roberta João David de MASI, Evaldo Dacheux de MACEDO FILHO, Nicole AMADEU, Fernanda Laís SAITO, Letícia OYAMA, João Pedro Ribeiro BAPTISTA, Guilherme Simas do Amaral CATANI,

Abstract

Introduction: The new coronavirus pandemic has given rise to several systemic pathologies correlated to the viral infection, which has flu-like symptoms in the upper airways. There are reports in the literature, however, that mention signs of dysphonia, odynophagia and pharyngeal globus sensation after infection. The larynx, an organ that is part of the airway, is possibly the affected location to set off those symptoms. Objective: To examine the laryngeal alterations in patients after SARS-CoV-2 infection. Methods: This was an observational and analytical cross-sectional study in which the medical records of patients with the aforementioned complaints, and who underwent videolaryngoscopy, were reviewed. The statistical level of significance was set at p<0.05. Results: 34,143 medical records were reviewed, and a final result of 57 patients with the aforementioned complaints and videolaryngoscopy examination was found. The age, analyzed on the socioeconomic profile, was significant in the performed review. Out of the laryngeal alterations, hypotonia, fusiform glottal gap (p<0.001) and triangular glottal gap were significant. Laryngeal alterations were also significant in patients hospitalized for COVID-19. Discussion: These findings must be the main reason for post-COVID-19 hypokinetic dysphonia, due to probable damage to the recurrent laryngeal nerve.
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Keywords

Introduction: The new coronavirus pandemic has given rise to several systemic pathologies correlated to the viral infection, which has flu-like symptoms in the upper airways. There are reports in the literature, however, that mention signs of dysphonia, odynophagia and pharyngeal globus sensation after infection. The larynx, an organ that is part of the airway, is possibly the affected location to set off those symptoms. Objective: To examine the laryngeal alterations in patients after SARS-CoV-2 infection. Methods: This was an observational and analytical cross-sectional study in which the medical records of patients with the aforementioned complaints, and who underwent videolaryngoscopy, were reviewed. The statistical level of significance was set at p<0.05. Results: 34,143 medical records were reviewed, and a final result of 57 patients with the aforementioned complaints and videolaryngoscopy examination was found. The age, analyzed on the socioeconomic profile, was significant in the performed review. Out of the laryngeal alterations, hypotonia, fusiform glottal gap (p<0.001) and triangular glottal gap were significant. Laryngeal alterations were also significant in patients hospitalized for COVID-19. Discussion: These findings must be the main reason for post-COVID-19 hypokinetic dysphonia, due to probable damage to the recurrent laryngeal nerve.

How to cite

Masi RJD, Macedo Filho ED, Amadeu N, Saito FL, Oyama L, Baptista JPR, Catani GSA. Analysis of laryngeal alterations in patients after SARS-COV-2 infection. J Contemp Dis Adv Med. 2022 May-Aug;1(2):114-22.

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